Pulmonary vasodilation in the rat by insulin in vitro could indicate potential hazard for inhaled insulin
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study of cohesive devices in the textbook of english for the students of apsychology by rastegarpour
this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
Inhaled NO and pulmonary vasodilation.
To the Editor: Hare et al concluded that inhaled nitric oxide (NO) caused selective pulmonary vasodilation in patients receiving left ventricular assist device support and that this accounted for the increase in mean left atrial pressure, which they considered a beneficial hemodynamic effect. The evidence for pulmonary vasodilation was that pulmonary vascular resistance (PVR) decreased. However...
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Although insulin-mediated vasodilation is impaired in insulin resistance, the mechanisms of this are unknown. We investigated factors mediating vasoactive responses to insulin in control and insulin-resistant rats. Responses to insulin in small mesenteric arteries from control and insulin-resistant rats were investigated after blocking endothelin-A receptors, cyclooxygenase, nitric oxide syntha...
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OBJECTIVE This study evaluated pharmacokinetic and glucodynamic responses to AIR inhaled insulin relative to subcutaneous insulin lispro, safety, pulmonary function, and effects of salbutamol coadministration. RESEARCH DESIGN AND METHODS Healthy, mildly asthmatic, and moderately asthmatic subjects (n = 13/group, aged 19-58 years, nonsmoking, and nondiabetic) completed this phase I, open-label...
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Meal-induced sensitization to the dynamic actions of insulin results from the peripheral actions of a hormone released by the liver (hepatic insulin sensitizing substance or HISS). Absence of meal-induced insulin sensitization results in the pathologies associated with cardiometabolic risk. Using three protocols that have previously demonstrated HISS metabolic action, we tested the hypothesis t...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2003
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-003-1172-y